Publications

An up to date publication list is available via Pubmed

Olga Bondareva, Jesús Rafael Rodríguez-Aguilera, Fabiana Oliveira, Longsheng Liao, Alina Rose, Anubhuti Gupta, Kunal Singh, Florian Geier, Jenny Schuster, Jes-Niels Boeckel, Joerg M Buescher, Shrey Kohli, Nora Klöting, Berend Isermann, Matthias Blüher, Bilal N Sheikh: Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity. Nature Metabolism (2022)

Paulina Elena Stürzebecher, Susan Kralisch, Marie Ruth Schubert, Vanina Filipova, Annett Hoffmann, Fabiana Oliveira, Bilal N Sheikh, Matthias Blüher, Alexander Kogel, Markus Scholz, Karoline Elizabeth Kokot, Stephan Erbe, Jasmin Marga Kneuer, Thomas Ebert, Mathias Fasshauer, Konstanze Miehle, Ulrich Laufs, Anke Tönjes, Jes-Niels Boeckel: Leptin treatment has vasculo-protective effects in lipodystrophic mice. PNAS (2022)

Karoline E Kokot, Jasmin M Kneuer, David John, Sabine Rebs, Maximilian N Möbius-Winkler, Stephan Erbe, Marion Müller, Michael Andritschke, Susanne Gaul, Bilal N Sheikh, Jan Haas, Holger Thiele, Oliver J Müller, Susanne Hille, Florian Leuschner, Stefanie Dimmeler, Katrin Streckfuss-Bömeke, Benjamin Meder, Ulrich Laufs and Jes-Niels Boeckel: Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs. Basic Research in Cardiology (2022)

Bilal N. Sheikh, Sukanya Guhathakurta, Tsz Hong Tsang, Marius Schwabenland, Gina Renschler, Benjamin Herquel, Vivek Bhardwaj, Herbert Holz, Thomas Stehle, Olga Bondareva, Nadim Aizarani, Omar Mossad, Oliver Kretz, Wilfried Reichardt, Aindrila Chatterjee, Laura J. Braun, Julien Thevenon, Herve Sartelet, Thomas Blank, Dominic Grün, Dominik von Elverfeldt, Tobias B. Huber, Dietmar Vestweber, Sergiy Avilov, Marco Prinz, Joerg M. Buescher and Asifa Akhtar: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nature Cell Biology (2020)

Olga Bondareva and Bilal N. Sheikh: Vascular homeostasis and inflammation in health and disease – lessons from single cell technologies. International Journal of Molecular Sciences (2020)

Aline Gaub, Bilal N. Sheikh, M. Felicia Basilicata, Marie Vincent, Mathilde Nizon, Cindy Colson, Matthew J. Bird, James E. Bradner, Julien Thevenon, Michael Boutros, Asifa Akhtar: Evolutionary conserved NSL complex/NRD4 axis controls transcription via histone acetylation. Nature Communications (2020)

Bilal N. Sheikh, Olga Bondareva, Sukanya Guhathakurta, Sagar, Nadim Aizarani, Dominic Grün, Lutz Hein and Asifa Akhtar:Systemic identification of cell-cell communication in the developing brainiScience (2019)

Bilal N. Sheikh, Sukanya Guhathakurta and Asifa Akhtar: The Non-specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis. EMBO reports (2019)

Bilal N. Sheikh and Asifa Akhtar: Many lives of KATs – detectors, integrators and modulators of the cellular environment.Nature Reviews Genetics (2019)

Helen M. McRae, Alexandra L. Garnham, Yifang Hu, Matthew T. Witkowski, Mark A. Corbett, Mathew P. Dixon, Rose E. May, Bilal N. Sheikh, William Chiang, Andrew J. Kueh, Tan A. Nguyen, Kevin Man, Renee Gloury, Brandon J. Aubrey, Andreas Strasser, Edwin D. Hawkins, Stephen Wilcox, Jozef Gécz, Axel Kallies, Matthew P. McCormack, Gordon K. Smyth, Anne K. Voss and Tim Thomas: PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia. Blood (2019)

Stephanie Grabow, Andrew J. Kueh, Francine Ke, Hannah K. Vanyai, Bilal N. Sheikh, Michael A. Dengler, William Chiang,Samantha Eccles, Ian M. Smyth, Lynelle K. Jones, Frederic J. de Sauvage, Mark Scott, Lachlan Whitehead, Anne K. Voss and Andreas Strasser: Subtle changes in the levels of BCL-2 proteins cause severe craniofacial abnormalities. Cell Reports(2018) 

Jonathan B. Baell, David J. Leaver, Stefan J. Hermans, Gemma L. Kelly, Margs S. Brennan, Natalie L. Downer, Nghi Nguyen, Johannes Wichmann, Helen M. McRae, Yuqing Yang, Ben Cleary, H. Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah K. Vanyai, Maria I. Bergamasco, Rose E. May, Bethany K. Davey, Kimberly J. Morgan, Andrew J. Sealey, Beinan Wang, Natasha Zamudio, Stephen Wilcox, Alexandra Garnham, Bilal N. Sheikh, Brandon. J. Aubrey, Karen Doggett, Matthew C. Chung, Melanie de Silva, John Bentley, Pat Pilling, Meghan Hattarki, Olan Dolezal, Matthew Dennis, Hendrik Falk, Bin Ren, Susan A. Charman, Karen L. White, Jai Rautela, Andrea Newbold, Edwin D. Hawkins, Ricky W. Johnstone, Nicholas D. Huntington, Thomas S. Peat, Joan K Heath, Andreas Strasser, Michael W. Parker, Gordon K. Smyth, Ian P. Street, Brendon J. Monahan, Anne K. Voss, and Tim Thomas: Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumor growth. Nature (2018)

Bilal N. Sheikh, Donald Metcalf, Anne K Voss and Tim Thomas: MOZ and BMI1 act synergistically to maintain hematopoietic stem cellsExperimental Hematology (2017)

Isobel D. Lawrenson, Danielle L. Krebs, Edmond M. Linossi, Jian-Guo Zhang, Tamara J. McLennan, Caitlin Collin, Helen M. McRae, Tatiana B. Kolesnik, Katrina Koh, Joanne M. Britto, Andrew J. Kueh, Bilal N. Sheikh, Farrah El-Saafin, Nicos A. Nicola, Seong-Seng Tan, Jeffrey J. Babon, Sandra E. Nicholson, Warren S. Alexander, Tim Thomas and Anne K. Voss: Cortical layer inversion and deregulation of Reelin signaling in the absence of SOCS6 and SOCS7. Cerebral Cortex (2017)

Bilal N. Sheikh, Yuqing Yang, Jaring Schreuder, Susan K. Nilsson, Rebecca Bilardi, Sebastian Carotta, Helen M. McRae, Donald Metcalf, Anne K. Voss and Tim Thomas: MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells. Blood (2016)

Bilal N. Sheikh, Wibke Bechtel-Walz, Jacopo Lucci, Oleksandra Karpiuk, Iris Hild, Björn Hartleben, Julia Vornweg, Abdullah H. Sahyoun, Vivek Bhardwaj, Thomas Stehle, Sarah Diehl, Oliver Kretz, Anne K. Voss, Tim Thomas, Thomas Manke, Tobias B. Huber and Asifa Akhtar: MOF maintains transcriptional programs required to protect cells against stress. Oncogene (2016) 

Bilal N. Sheikh, Natalie L. Downer, Belinda Phipson, Hannah K. Vanyai, Andrew J. Kueh, Davis J. McCarthy, Gordon K. Smyth, Tim Thomas and Anne K. Voss: MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo. Proceedings of the National Academy of Sciences – PNAS (2015) 

Bilal N. Sheikh, Stanley C. W. Lee, Farrah El-Saafin, Hannah K. Vanyai, Yifang Hu, Stephanie Grabow, Andreas Strasser, Stephen L. Nutt, Warren S. Alexander, Gordon K. Smyth, Anne K. Voss and Tim Thomas: MOZ regulates B cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development. Blood (2015) 

Bilal N. Sheikh, Belinda Phipson, Farrah El-Saafin, Hannah K. Vanyai, Natalie L. Downer, Matthew J. Bird, Andrew J. Kueh, Rose E. May, Gordon K. Smyth, Anne K. Voss and Tim Thomas: MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway. Oncogene (2015)

Bilal N. Sheikh: Crafting the Brain – Role of Histone Acetyltransferases in neural development and disease. Cell Tissue Research (2014)

Bilal N. Sheikh, Natalie L. Downer, Andrew J. Kueh, Tim Thomas and Anne K. Voss: Excessive vs. physiologically relevant levels of Retinoic Acid in ES cell differentiation. Stem Cells (2014).

Anne K. Voss, Hannah K. Vanyai, Caitlin Collin, Mathew P. Dixon, Tamara McLennan, Bilal N. Sheikh, Peter Scambler and Tim Thomas: MOZ regulates the Tbx1 locus and Moz mutation partially phenocopies DiGeorge syndrome. Developmental Cell(2012).

Bilal N. Sheikh, Mathew P. Dixon, Tim Thomas and Anne K. Voss: Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells. Journal of Cell Science (2012)

Michael Kraft, Ion Cristian Cirstea, Anne Kathrin Voss, Tim Thomas, Ina Goehring, Bilal N. Sheikh, Lavinia Gordon, Hamish Scott, Gordon K. Smyth, Mohammad Reza Ahmadian, Udo Trautmann, Martin Zenker, Marco Tartaglia, Arif Ekici, André Reis, Helmuth-Guenther Dörr, Anita Rauch and Christian Thomas Thiel: Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome–like phenotype and hyperactivated MAPK signaling in humans and mice. Journal of Clinical Investigation (2011)

Anne K. Voss, Joanne M. Britto, Mathew P. Dixon, Bilal N. Sheikh, Caitlin Collin, Seong-Seng Tan and Tim Thomas: C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment. Development (2008)